Deep Panning: Steps towards Probing the IgOme

Deep Panning: Steps towards Probing the IgOme

BACKGROUND Polyclonal serum consists of vast collections of antibodies, products of differentiated B-cells. The spectrum of antibody specificities is dynamic and varies with age, physiology, and exposure to pathological insults. The complete repertoire of antibody specificities in blood, the IgOme, is therefore an extraordinarily rich source of information-a molecular record of previous encount...

I-25: New Steps towards The Artificial Ovary

Background: In recent years, transplantation of cryopreserved ovarian tissue has proved to be a promising approach to restore fertility in cancer patients. However, such a procedure cannot be carried out in women at risk of ovarian involvement due to the threat of reintroducing malignant cells. The aim of this study was therefore to create an artificial ovary as an alternative to restore fertil...

First steps towards adaptive deep brain stimulation in Parkinson’s disease

Introduction: Deep brain stimulation (DBS) is used to treat Parkinson's disease (PD), when medical therapies are not efficient enough [1]. DBS requires the implantation of stimulation electrodes reaching into deep brain areas, commonly into the subthalamic nucleus (STN) that is one of the relay of the extrapyramidal circuit. Electrical pulses are sent on a fixed regular pace. Despite the proven...

Seven Steps Towards the Classi

Steps towards knowledge science

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